Abstract

Paederia foetida commonly known as skunk vine, is commonly used as a medicinal plant used in various countries. Current research has shown that P. foetida has a lot of beneficial properties like antimicrobial properties, antimicrobial properties, and inflammatory properties. It has been found to be very effective against rheumatoid arthritis. Where commonly used phenylbutazone for arthritis only reduces inflammation by about 29%, P. foetida leaves extract can reduce up to 52%. Studies show a class of compounds called peaderosides are responsible for its anti-inflammatory effects and other medicinal properties. Though, being known for its properties, it is hard to extract and due to its non-polar nature. Along with being hydrophobic in nature. It shows low penetrability in human skin. Herein we have brought forward a potential solution by formulating it into nano formulation using its extract. The P. foetida leaf’s alcohol and water extract is used for synthesizing nanoparticles using a GRASS material. The P. foetida leaf extract nanoparticles (LNP) were characterized using Dynamic light scattering, zetapotential, SEM and UV vis spectroscopy. Along with that minimum inhibition concentration (MIC), radical scavenging activity, cytotoxicity and invitro anti-inflammatory assay were conducted on LNP This opens a new potential for introducing a drug which can be used for inflammation without any side effects.

Biography

Preeti Maiti is a PhD student in the Department of Chemistry at the University of Central Florida (UCF), Orlando, Florida, USA, and is affiliated with the Nanoscience and Nanotechnology Center. Her research focuses on developing new formulations as delivery agents for agricultural applications, with the aim of improving the efficiency and effectiveness of agrochemical delivery systems. She holds a bachelor’s degree in Agriculture, which provides a strong foundation for her current research in plant-related applications. By integrating principles of chemistry and agricultural science, her work contributes to advancing innovative solutions for sustainable agricultural practices.

Abstract

Background: Patients with coronary heart disease (CAD) do not regularly take exercise after receiving a percutaneous coronary intervention (PCI). This may easily cause heart attack again. Until now, there is a lack of study to develop an artificial intelligence (AI) skeleton recognition home-based physical activity for CAD patients, and yet, no study tests the effects of it.
Methods: A pilot study of quasi-experimental design of 30 CAD patients who received PCIs were recruited. An AI skeleton recognition home-based physical activity and mobile care App were then developed by the researchers as an innovative intervention and alternative medicine. The experimental group(n=15) received one-month AI home-based physical activity, and the control group (n=15) had standard medical care (SMC). Demographic questionnaire, Duke Activity Status Index (DASI), and Quality of Life (QoF) questionnaires, were measured before PCI and 1 month after discharge. The Cronbach’s α of DASI and QoF, were .72 and .84, showing good reliability. Independent t-test and Chi square test were used for data analysis.
Results:The mean (SD) age of AI App group and SMC group was 54.2±7.43 and 62.19±8.85, respectively. One month after discharge, both groups had no significant difference in daily activity and quality of life (p>.05). However, AI APP group showed a significant improvement in the physical component summary score (p<.05) than those before the PCI.
Conclusions:The AI skeleton recognition home-based physical activity demonstrates a good support and alternative medicine for CAD patients in regular exercise. AI home-based physical activity can help PCI patients in improving heart function, exercise habits, and quality of life after PCI. Also, it can save patient’s time and money for hospital-based rehabilitation. However, further studies with large sample sizes and follow-up period are recommended.
Key words: artificial intelligence (AI), skeleton recognition, home-based physical activity, mobile application (App), coronary artery diseases (CAD)
Abstract Summary
1. An AI skeleton recognition home-based physical activity and App was developed by the researchers for patients with coronary artery diseases.
2. AI skeleton recognition home-based physical activity demonstrates a good support for patients with coronary artery diseases who requiring regular exercise at home.

Biography

Pro. Shu-Fen Su, is a nursing professor of the National Taichung University of Science and Technology, Taiwan. She has been teaching cardiovascular and critical care nursing in the university for 25 years. Her specific nursing field are critical care nursing, cardiovascular nursing, nurse practitioner, evidence based research, quantitative research, and qualitative research, telemedicine

Abstract

Background: Resident physician burnout is a long-standing issue in medical education with the COVID-19 pandemic causing significant additional burnout burden. Navines et. al. (2021) found current burnout rates of residents as high as 76% (vs 50% prior). Implementation of mindfulness programs has been shown to improve physician wellness, decrease burnout, & create environments of resilience (Romcevich et.al 2018, Ireland,et. al 2017). Epstein et. al. (2021) implemented a 4-day mindfulness workshop for physicians, improving emotional exhaustion, depersonalization, & patient-centered care. While mindfulness has recently come to the forefront of wellness, few studies describe feasible, longitudinal programs focused on resident wellness. Programs like Search Inside Yourself (SIY) teach mindfulness, emotional intelligence & leadership skills & may assist with mitigating burnout.
Objective: To assess a feasible, longitudinal mindfulness program (SIY) for resident physicians to combat burnout & stress; build resilience; & improve self-care.
Design/Methods: After completion of SIY training, Dr. Sawni (pediatrician) & Dr. Wolf (psychologist), taught a modified version to Pediatric & Medicine-Pediatric residents at Hurley Hospital, Flint MI. It consisted of 12 hours, split over 3 consecutive sessions. Pre & post-surveys were given,(n=25) assessing demographics, wellness, & program evaluation. Desired responses to 29 wellness questions (combining Strongly Agree/Agree, Very Often/Often, Strongly Disagree/Disagree, or Rarely/Never) were compared pre- to post-training. The study was approved by Hurley Hospital IRB.
Results: Of the 29 wellness questions,10 items had a positive change by at least 10 percentage points. There were 5 items, related to distractibility, that decreased by at least 10 points, indicating that mindfulness helps with being more present. After the program, 93% of attendees said they were Satisfied/Very Satisfied with the mindfulness program and 93% agreed that the material was relevant to current challenges. The majority (86%) reported feeling ready to apply what they learned.
Conclusions: Mindfulness as an approach to mitigate burnout & stress has been successful with resident physicians in limited previous studies. Teaching & incorporating mindfulness is feasible & can be introduced as part of the core residency curriculum. This pilot study presents a feasible way to incorporate mindfulness training within the educational context. Though the number of completed surveys was relatively low, the overall impact of the study was large. Limitations include a small sample size & a limited number of sessions. Future programs will include similar mindfulness interventions to support wellness longitudinally.

Biography

Dr. Anju Sawni M.D. FAAP, FSAHM is the Director of Adolescent Medicine at Hurley Children’s Hospital/Hurley Medical Center, Flint MI & Associate Professor of Pediatrics Department of Pediatrics & Human Development, Michigan State University/College of Human Medicine, Lansing, MI. Her interest not only includes Adolescent Health, but also Integrative Medicine. She is a member of the AAP section on integrative pediatrics. She has done research, published several papers & written chapters on Adolescent health & Integrative Medicine, and presented many lectures/workshops; nationally, statewide & locally. She integrates mind/body therapies such as relaxation techniques/self-hypnosis/mindfulness meditation, yoga, nutritional supplements, etc. in her adolescent practice. She has trained in mindfulness with Dr. Ronald Epstein, the University of Rochester, Mindfulness in Medicine Program, Search Inside Yourself Institute that promotes Mindfulness, Emotional Intelligence & Leadership & Awake Network; mindful health care summit as well as given several lectures on “Mindfulness in Medicine”. She incorporates/teaches mindfulness in medicine as part of the professionalism series to Hurley hospital & McLaren Health system residents. She serves on the board of directors of the Crim Foundation Mindfulness Initiative, Flint MI. She practices meditation/mindfulness/yoga in her personal and professional life.